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KMID : 0363220100480030232
Korean Journal of Dermatology
2010 Volume.48 No. 3 p.232 ~ p.236
A Case of Erythrodermic Mycosis Fungoides Treated with Gemcitabine
Yang Ji-Hye

Kang Yoon-Koo
Chang Sung-Eun
Lee Mi-Woo
Choi Jee-Ho
Moon Kee-Chan
Lee Deok-Woo
Won Chong-Hyun
Abstract
Erythrodermic mycosis fungoides (MF) denotes a condition in which erythroderma occurs in patients with otherwise typical clinical features of MF. Gemcitabine is a novel treatment regiment for MF. A 16-year-old boy presented in the hospital with skin lesions that showed generalized erythema with scaling, several plaques, and nodules with ulceration on the extremities and trunk. He was diagnosed with erythrodermic MF. His lesions did not improve with methotrexate (7.5 mg/week) and PUVA for 6 months, so his treatment regimen was changed to systemic gemcitabine therapy (1,000 mg/m2 per week). After 6 cycles of gemcitabine, his skin lesions disappeared. We report a case of erythrodermic MF treated by gemcitabine. (Korean J Dermatol 2010;48(3):232¡­236)
KEYWORD
Erythrodermic mycosis fungoides, Gemcitabine
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